Project B19

The physiology and pathophysiology of aldosterone production in the pig

Principal Investigators

Prof. Dr. med. vet.
Eckhard Wolf

Ludwig-Maximilians-Universität Munich

Institute of Molecular Animal Breeding and Biotechnology, Gene Centre and Department of Veterinary Sciences

ewolf[at]genzentrum.lmu.de

PD Dr. med. vet.
Elisabeth Kemter

Ludwig-Maximilians-Universität Munich

Institute of Molecular Animal Breeding and Biotechnology, Gene Centre and Department of Veterinary  Sciences

kemter[at]genzentrum.lmu.de

PhD
Tracy Ann Williams

Ludwig-Maximilians-Universität Munich

Medizinische Klinik und Poliklinik IV

tracy.williams[at]med.uni-muenchen.de

Aims

(I) Identify biological mechanisms that regulate aldosterone production in the pig adrenal cortex

(II) Generate a pig transgenic model of PA by integration of a KCNJ5 mutation

Publications (CRC/TRR 205 included)