The projects of the CRC/TRR 205 are divided into two research areas A and B. Both research areas involve investigations of pathological conditions characterised by abnormal proliferation or survival of cells arising from either the adrenal medulla or cortex.
Research Area A, “Adrenal and systemic disease” focuses on cellular interactions within the adrenal microenvironment and the bidirectional crosstalk between adrenals and major systemic functions in the context of systemic diseases, such as obesity and inflammation. This research area centres it’s attention on mechanisms regulating adrenal plasticity and regeneration.
Research Area B, “Adrenal-related tumours” focuses on adrenal tumours and in particular their pathogenesis, paving the way for the development of an improved approach for diagnosis and therapy.
The knowledge gained from each research area will provide insights into the other, leading to a new detailed overall knowledge of the adrenal.
For detailed information on the projects please choose the single project in the sidebar.